Savannah Guthrie and her siblings, sister Catherine and brother Todd, making a statement regarding their mother Nancy’s disappearance.

They alluded to the reports of a possible kidnapper, saying they are “ready to talk.” Instagram / Savannah Guthrie

The “Today” show host delivered the tearful statement while flanked by her siblings Annie and Cameron Guthrie in a video shared to Instagram Wednesday night.

Savannah also touched on the reports of a ransom letter that was sent to Tucson-area outlets and TMZ, which police haven’t yet verified.

“As a family, we are doing everything that we can. We are ready to talk,” she said.

Savannah and Annie both spoke directly to their ailing mother, in hopes she was listening in somewhere.

Nancy Guthrie has been missing for the past four days. Facebook/Savanah Guthrie

“Mommy, if you are hearing this, you are a strong woman. You are God’s precious daughter, Nancy. We believe and know that even in this valley, he is with you. Everyone is looking for you, Mommy. Everywhere. We will not rest. Your children will not rest until we are together again,” Savannah choked through tears.

“Mama, mama, if you’re listening, we need you to come home. We miss you,” Annie added.

Cameron, the family’s eldest, could only say: “We love you Mom, stay strong, come home.”

Nancy was reported missing on Sunday after she failed to show up to church. She suffers from a heart condition that requires her to take daily medication to stay alive and “not to suffer,” Savannah said.